Edaravone Dexborneol Sublingual Tablet for the PSCI in Acute Ischemic Stroke Patients

Inclusion criteria

• ✓. Age ≥ 40 years and ≤ 80 years, male or female.
• ✓. Diagnosed as ischemic stroke, no significant pre-stroke functional disability (mRS score ≤ 1prior to stroke onset).
• ✓. The National Institutes of Stroke Scale score ≤ 20 points.
• ✓. Time from onset to obtained informed consent form is within 7 days (including 7 days).
• ✓. Presence of cognitive dysfunction at screening, i.e., MoCA scale score \< 22.
• ✓. Patients with good cognitive function prior to stroke, without significant cognitive dysfunction and dementia.
• ✓. Education level: primary school or above, and can complete the cognitive function test required per investigator's judgement.
• ✓. female subjects of childbearing potential and male subjects whose female partners are of childbearing potential must be willing to and use contraception during the study treatment and within 30 days after the last dose of study drug and have no plans to donate sperm or eggs; female subjects of childbearing potential will have a negative pregnancy test;

Exclusion criteria