CompletedEarly Phase 1

Immediate Post-Operative Anesthesia With Either Lidocaine or Bupivacaine

United States72 participantsStarted 2022-06-06

Plain-language summary

Immediate post-suturing administration of either one of two dental anesthetic solutions or a placebo prior to dismissal.

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

✓Patients who have undergone a comprehensive periodontal evaluation and treatment plan not related to participation in this study and…
✓. require flap surgery of 2 to 5 teeth in a continuous site (including flap debridement, flap osseous, extractions, and Guided Tissue Regeneration (GTR) procedures), and…
✓. require IV sedation and local anesthesia or local anesthesia only…
✓. in either the maxillary or mandibular arch.

✕. Pregnancy, or those planning to become pregnant
✕. allergy or any medical issue using Lidocaine or Bupivacaine
✕. inability to take non-steroidal anti-inflammatory drugs (NSAIDS) or acetaminophen
✕. non-English speaking
✕. not possessing an I-phone or Android device
✕. patients requiring narcotic for IV sedation
✕. patients requiring either IV or oral steroids during the perioperative period

Change in pain using Visual Analog Scale (VAS)

Timeframe: Baseline to 48 hours

Number of Ibuprofen administered

Timeframe: Baseline to 48 hours

Number of Tylenol administered

Timeframe: Baseline to 48 hours

NCT IDNCT06293807

SponsorThe University of Texas Health Science Center at San Antonio

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-04-16