Exercise for Improving Radiotherapy Efficacy in Rectal Cancer (NCT06292975) | Clinical Trial Compass
WithdrawnNot Applicable
Exercise for Improving Radiotherapy Efficacy in Rectal Cancer
Stopped: Although patients were screened, only two met the eligibility criteria within the available timeframe. None of the two eligible patients agreed to participate in the study, as a result, no patients were enrolled in the study.
United Kingdom0Started 2024-09-17
Plain-language summary
This is a single arm feasibility study of exercise for improving short- course neoadjuvant radiotherapy efficacy in people diagnosed with locally advanced rectal cancer. The study aims to recruit up to 30 patients from the Queen's Centre for Oncology and Haematology of Castle Hill Hospital, Cottingham, diagnosed with locally advanced rectal cancer. Consenting patient's will be provided with a 7 weeks course of structured aerobic exercises and resistance training in the periods before, during and after their radiotherapy treatment. The patients will be followed up for 6 months post short course neoadjuvant radiotherapy, with a total of 3 assessment periods.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* 18 years or older
* Have been diagnosed with locally advanced rectal cancer using MRI (Magnetic Resonance Imaging) and histological finding,
* Have been offered short-course neoadjuvant radiotherapy in the Queens Centre, Castle Hill Hospital
* Willing and able to comply with all study requirements
* Able and willing to voluntarily give informed consent to take part.
Exclusion Criteria:
* Inability to understand basic written and spoken English, as research materials will all be written in English.
* Any movement deficiencies limiting ability to engage in exercise.
* Impaired cognition and/or capacity limiting ability to provide informed consent.
* Cardiovascular and/or cardiopulmonary conditions that will impede ability to safely perform exercise.
* Severe psychiatric disorders.
* With any other health condition which oncologists and research team agrees will impede ability to safely perform exercises.
* Presence of metastatic cancer.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Recruitment rate
Timeframe: This will be monitored in the total 6months of participants engagement if the study
2
Attendance rate
Timeframe: This will be monitored in the total 6months of participants engagement if the study
3
withdrawal rate
Timeframe: This will be monitored in the total 6months of participants engagement if the study