A Predictive Model and Scoring System for Severe Complications After Endovascular Thrombectomy (NCT06290076) | Clinical Trial Compass
CompletedNot Applicable
A Predictive Model and Scoring System for Severe Complications After Endovascular Thrombectomy
China1,500 participantsStarted 2020-01-01
Plain-language summary
To establish a predictive model and scoring system for predicting severe complications after thrombectomy. This scoring system can be used to identify high-risk patients after endovascular thrombectomy, guide the early use of adjunctive interventions, and provide reference for future clinical trials.
Who can participate
Age range18 Years
SexALL
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Inclusion criteria
✓. Symptoms and signs compatible with ischemia in the anterior circulation
✓. Internal carotid artery occlusion or middle cerebral artery M1 and M2 segment occlusion confirmed by computed tomographic angiography (CTA)/ magnetic resonance angiography (MRA)/ digital subtraction angiography (DSA)
✓. Premorbid mRS ≤1;
✓. National Institutes of Health Stroke Score (NIHSS) ≥6 at admission;
✓. Onset to puncture time ≤24h;
✓. Treated with thrombectomy resulting in mTICI score ≥2b at end of the procedure.
Exclusion criteria
✕. Intracranial hemorrhage, aneurysm, and arteriovenous malformation before endovascular thrombectomy;
✕. Perioperative complications, including dissection and arterial perforation;
✕. Anticipated life expectancy \<3 months;
✕. Critical baseline clinical, laboratory and imaging data are missing;
✕. Lack of follow-up results within 72 hours and 90 days after thrombectomy;
✕. Pregnant or lactating women;
✕. Severe systemic diseases (e.g. advanced cancer), potentially interfering with prognosis;