This trial is a single-center, prospective study. The study proposes to recruit 20 patients with solar lentigo on both sides of the face. Patients are to be treated with high-intensity focused ultrasound (MFUS One, Hunan Peninsula Medical Technology Co., Ltd., China). oth sides of the face received treatment with identical parameters. The facial images are collected with dermoscope (DermLite DL4,3 Gen Inc., San Juan Capistrano, CA, USA), VISIA® (Canfield Company, USA) and a two-photon microscope (Transcend Vivoscope, China). For dermoscopy images, ImageJ software was then utilized to perform Lab\* conversion on both the lesional area and the surrounding non-lesional areas. Measurements of transepidermal water loss (TEWL) values, skin elasticity and related images at the same location, along with adverse events, physician and subjective global aesthetic improvement scale scores are recorded before and at week2, week 4, week6 and week8.
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Lab* Values of Lesional Area Using Dermoscopy and ImageJ
Timeframe: week0, week2, week4, week6 and week8
Physician Global Aesthetic Improvement Scale Score
Timeframe: week2, week4, week6 and week8
Subjective Global Aesthetic Improvement Scale Score
Timeframe: week2, week4, week6 and week8
Transepidermal Water Loss (TEWL) Measurement of Lesional Area
Timeframe: week0, week2, week4, week6 and week8
Skin Elasticity Measurement of Lesional Area
Timeframe: week0, week2, week4, week6 and week8