CBCT vs OPT on the Oral Health Status at 12 Months of Patients Hospitalized for Infective Endocar… (NCT06269679) | Clinical Trial Compass
RecruitingNot Applicable
CBCT vs OPT on the Oral Health Status at 12 Months of Patients Hospitalized for Infective Endocarditis.
France170 participantsStarted 2024-12-18
Plain-language summary
1\. Infective Endocarditis (IE) is a rare and serious disease with high morbidity and mortality; 2. Streptoccoci of oral origin are the second more frequent microorganisms responsible for IE; 3. Oral Infectious Foci (OIF) are underdetected using the current recommended clinical examination/Orthopantomogram (OPT) approach; 4. Cone Beam Computed Tomography (CBCT) has a better sensitivity and sensibility to detect OIF than OPT; 5. To date, no study has been performed to assess the potential benefit of a clinical examination/CBCT approach on the oral health status in IE patients.
Thus, conducting a randomized controlled trial is highly desirable to assess the potential impact of a clinical examination/CBCT approach on the oral health status of patients hospitalized for IE and potentially to reduce IE new episodes.
Who can participate
Age range18 Years – 100 Years
SexALL
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Inclusion criteria
✓. Patients hospitalized or recently hospitalized for definite IE according to the 2015 ESC classification, naive patients for dental examination and imaging, whatever the IE responsible microorganism;
✓. Patients with a stable clinical state, meaning stabilized IE patients out of the critical phase, compatible with the performance of an OPT and a CBCT;
✓. Patients whose life expectancy is expected to be longer than 6 months;
✓. Patients who agree to visit the dental department of the hospital to carry out OIF eradication or at his/her personal dentist;
✓. Patients over 18 years old;
✓. Patients affiliated to a Social Security or a health insurance scheme;
✓. Patients who have given informed consent to participate to the study.
Exclusion criteria
✕. OPT or CBCT already performed before the inclusion of the patients in the study and available for the investigator during the patient's hospitalization.