Diet and Depression (NCT06252701) | Clinical Trial Compass
CompletedNot Applicable
Diet and Depression
United States20 participantsStarted 2024-06-18
Plain-language summary
This study is a pilot open label crossover trial to assess the feasibility and acceptability of reducing ultra- processed foods (UPF) in a personalized manner from the diets of patients with major depressive disorder who eat a large percentage of UPF.
Who can participate
Age range18 Years – 80 Years
SexALL
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Inclusion Criteria:
* 18-80 year olds (inclusive), all race/ethnic groups
* Willing to not change psychotropic medication or psychotherapy regimen during the study
* Willing and able to come to UCSF for in person visits two times
* Ability to speak and read English and answer participant surveys
Exclusion Criteria:
* Psychiatric hospitalization in past 3 months
* Active suicidal ideation with intent and plan or scoring a 3 or higher on the Columbia suicide severity rating scale (C-SSRS)
* In a current severe mood state when entering the study that would prohibit compliance with study visits or dietary program
* Known GI abnormalities or known GI medical problems (diarrhea, chronic intestinal disease, toxic megacolon, ileum) or known swallowing or chewing disorders or issues
* Anticipating or planning any major changes in physical activity or sleep during the study
* Pregnant or planning to be pregnant during the study
* Breastfeeding or planning to breastfeed during the study