Adapting and Piloting Behavioral Activation for Veterans With Alcohol Use Disorder and Posttrauma… (NCT06249386) | Clinical Trial Compass
CompletedNot Applicable
Adapting and Piloting Behavioral Activation for Veterans With Alcohol Use Disorder and Posttraumatic Stress Disorder
United States10 participantsStarted 2025-01-17
Plain-language summary
The goal of this clinical trial is to compare an adaptation of Behavioral Activation, a behavioral intervention, to Relapse Prevention treatment, another behavioral intervention, in a sample of U.S. military veterans with co-occurring alcohol use disorder (AUD) and posttraumatic stress disorder (PTSD).
The primary aims of this study are to:
1. Adapt Behavioral Activation to treat veterans with AUD/PTSD,
2. Evaluate the feasibility, acceptability, and preliminary effects of Behavioral Activation for AUD/PTSD, and
3. Explore geospatial analysis as a new method for measuring AUD/PTSD recovery.
Participants will complete self-report and interview measures immediately before and immediately after treatment. Participants will also be asked to participate in passive geospatial assessment for 14-day periods immediately before and immediately after treatment. Participants will be randomized to treatment condition, which involves 8 sessions of either Behavioral Activation or Relapse Prevention, delivered individually by a trained study therapist.
Who can participate
Age range18 Years
SexALL
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Inclusion criteria
✓. Be a U.S. veteran,
✓. Be at least 18 years old,
✓. Meet Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria for current AUD,
✓. Report 3+ heavy drinking days (5+ drinks for men/4+ drinks for women) or 1+ heavy drinking week (15+ drinks men/8+ drinks women) in the past 30 days,
✓. Meet DSM-5 criteria for current PTSD or satisfy the definition of current subthreshold PTSD (i.e., up to one of symptom clusters B-E may fall below diagnostic threshold),
✓. Be fluent and literate in English, and
✓. Be able to provide voluntary, informed consent to participate.
Exclusion criteria
✕. Current mania/hypomania or current psychosis,
✕. Lifetime alcohol withdrawal-related seizures, delirium, or hallucinations,
✕
What they're measuring
1
Timeline Follow-Back (Alcohol Use)
Timeframe: Through study completion, an average of 3 months
2
Clinician-Administered PTSD Scale for DSM-5 (PTSD Severity)
Timeframe: Through study completion, an average of 3 months
✕. Current DSM-5 severe drug use disorder (DUD) except for severe tobacco use disorder,
✕. Psychotropic (including alcohol abstinence) medication changes within 30 days of study enrollment or plans to change medications during the study,
✕. Current/planned non-study BA for any disorder during the study, or
✕. Current/planned evidence-based psychotherapy for AUD, PTSD, or DUD during the study.