Histological Evaluation of Human Skin Bx to Assess the Effects of APR Tx as an Adjunct Procedure in Facelift Surgery

Inclusion Criteria: * Male or female subjects, ages 18 - 75 years old. * ASA Physical Status Classification System Class I and Class II subjects. * Planning to undergo a lower facelift procedure, with or without a neck lift, at the investigator's site. * Understands and accepts the obligation not to undergo any other procedures or treatments in the areas to be treated during study participation. * Absence of physical conditions unacceptable to the investigator. * Females of childbearing potential who are sexually active must be willing to use an approved method of birth control during study participation. * Willing and able to comply with protocol requirements, including study-required images/photos, assessments/measurements, and returning for follow-up visits. * Willing to release rights for the use of study photos, including in publication. * Able to read, understand, sign, and date the informed consent. * Able to communicate with the site via video and/or photographs, in the event of a virtual follow-up visit. Exclusion Criteria: * Subjects presenting with ASA Physical Status Classification System Classes III or higher. * Pregnant, lactating, or plans to become pregnant during study participation. * Known hypersensitivity or allergy to tumescent anesthetic (lidocaine/ epinephrine). * Known hypersensitivity or allergy to ibuprofen or other NSAIDS. * Active systemic or local skin disease that may alter wound healing. * Significant or uncontrolled medical condition that in…