AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. 18 years old and above;
✓. Subjects with moderate-to-severe nasolabial folds (3-4 level of WSRS scores) on both sides of the face
✓. Intended to be treated with PCL microsphere filler;
✓. Voluntarily participate in this test, cooperate with follow-up, and sign an informed consent form
Exclusion criteria
✕. Obvious acne scar, pigmentation, active infection, inflammation, tumor, precancerous lesion or unhealed wound in the intended injection area;
✕. Patients who have used permanent fillers (PMMA, hydrogel polymer, liquid silicone for injection, polyvinyl alcohol (PVA), bone cement, autologous fat, etc.) for nasolabial groove injection;
✕. Patients who have received semi-permanent fillers (polycaprolactone, L-polylactic acid, hydroxyapatite, platelet-rich plasma, etc.) injection treatment in nasolabial sulch area in the past 24 months;
✕. Patients who have received temporary fillers (hyaluronic acid, collagen, etc.) injection treatment in nasolabial groove in the past 12 months;
✕. Patients who have received botox injection treatment in nasolabial sulci in the past 6 months;
✕. The nasolabial groove has been treated with beauty plastic, focused ultrasound, chemical stripping, photoelectric (laser, photon, radio frequency) in the past 3 months;
✕. Use of hormones or immunosuppressants within the past 1 month;
✕. Subjects who have used anticoagulants in the last 2 weeks;