Breaking Sitting with High-intensity Interval Training for Brain Health (NCT06243016) | Clinical Trial Compass
RecruitingNot Applicable
Breaking Sitting with High-intensity Interval Training for Brain Health
United States54 participantsStarted 2024-05-07
Plain-language summary
This trial will examine whether interrupting 3.5 hours of sitting every 30 min with 6 min high intensity interval training (HIIT) breaks compared to light intensity interval training (LIIT) will improve brain health in cognitively normal older adults. This trial will test the feasibility of HIIT breaks to sitting. It will also address several important but unanswered questions: (1) Does interrupting sitting with short HIIT breaks improve frontoparietal function? (2) Can interrupting sitting with HIIT breaks improve cognitive functions?
Who can participate
Age range40 Years – 75 Years
SexALL
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Inclusion criteria
✓. Age 40-75 years
✓. BMI \<40 kg/m2
✓. Sedentary (≥ 6 h/day sitting by a survey question)
✓. Physically inactive adults based on the CSEP-PATH: Physical Activity and Sedentayr Behaviour Questionnaire (PASB-Q) Adult (low or medium physical activity range equivalent to less than 300 min of moderate intensity physical activity per week)
✓. Capable of exercising vigorously based on the Physical Activity Readiness Questionnaire (PARQ+)
✓. Has a medical clearance for maximal exercise and HIIT from a physician
✓. Normotensive or participant's blood pressure is controlled
✓. Intelligence quotient (IQ) ≥85
Exclusion criteria
✕. Physical disability or musculoskeletal disease prohibitive to vigorous exercise
Timeframe: Immediately before intervention, 2 x during the intervention (50 min and 120 min into the intervention), and immediately after the intervention