VE303 for Prevention of Recurrent Clostridioides Difficile Infection

Inclusion criteria

• ✓. Age ≥ 65 years
• ✓. Kidney dysfunction, defined as estimated creatinine clearance \< 60 mL/min/1.73 m\^2 at the time of the qualifying CDI episode
• ✓. History of regular use of a proton pump inhibitor (PPI) within the past 2 months and expectation of continued use of PPIs throughout the study
• ✓. History of a prior CDI episode between 6 and 12 months prior to enrollment
• ✓. Immunosuppression due to an underlying disease or its treatment
• ✓. Has undergone solid organ or hematopoietic stem cell transplantation
• ✓. New onset of ≥ 3 unformed bowel movements (ie, Types 5 to 7 on the Bristol stool scale) within 24 hours for 2 consecutive days
• ✓. CDI symptoms started within 4 weeks prior to initiation of standard of care (SoC) antibiotic therapy for CDI