Gynecologic Endoscopic Surgery of Female Motion Sickness Patients (NCT06232785) | Clinical Trial Compass
CompletedPhase 4
Gynecologic Endoscopic Surgery of Female Motion Sickness Patients
China66 participantsStarted 2022-02-01
Plain-language summary
The goal of this clinical trial is to compare the analgesic effect of sufentanil and ibuprofen and the incidence of vomiting, and to choose better postoperative analgesic drugs for motion sickness patients.in describe participant population. The main questions it aims to answer are:
* Whether this anesthesia method can meet the analgesic needs of gynecological laparoscopic surgery.
* Whether this anesthesia method can reduce the incidence of nausea and vomiting in patients with motion sickness after gynecological laparoscopic surgery.
Participants will use target-controlled infusion anesthesia combined with 0.8g ibuprofen injection.
Researchers will compare with use of target-controlled infusion combined with sufentanil to see if the incidence of nausea and vomiting is higher.
Who can participate
Age range18 Years – 60 Years
SexFEMALE
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Inclusion criteria
✓. Age 18-60 years old;
✓. Class I - II patients according to the American Society of Anesthesiologists classification;
✓. Body mass index : 20-27kg/㎡;
✓. non-life-threatening diseases of heart, lung, brain, liver, kidney and other important organs;
✓. No recent use of sedatives, opioids, non-steroidal drugs such as ibuprofen, antiemetic drugs.
✓. No history of digestive tract ulcer;
✓. Motion sickness patients undergoing gynecological endoscopic surgery under general anesthesia.
✓. Postoperative analgesia pump is not required.
Exclusion criteria
✕. Low weight, poor general state;
✕. general anesthesia drug allergy;
✕
What they're measuring
1
Comparison of postoperative nausea and vomiting between the two groups
Timeframe: From the end of surgery until 24 hours after surgery
2
Visual Analogue Score scores in postoperative resting state of patients in two groups
Timeframe: From the end of surgery until 24 hours after surgery
3
Comparison of vomiting between the two groups
Timeframe: From the end of surgery until 24 hours after surgery