BCAAs, Muscle Protein Synthesis and Glucose Uptake (NCT06218264) | Clinical Trial Compass
CompletedNot Applicable
BCAAs, Muscle Protein Synthesis and Glucose Uptake
Netherlands24 participantsStarted 2024-01-10
Plain-language summary
The present study aims to quantify the insulin sensitivity and the skeletal muscle protein synthetic response to consuming a test drink containing all amino acids or all amino acids except for BCAAs.
Who can participate
Age range18 Years – 35 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Aged from 18-35 years
* 18.5 \< Body mass index \< 30 kg·m2
* Recreationally active (performing non-competitive physical exercise at least one time per week for minimally 30 minutes)
Exclusion Criteria:
* Smoking
* Diabetes (Type 1, Type 2, or genetic form of diabetes)
* Any diagnosed cardiovascular (heart) disease or high blood pressure (≥140 mmHg systolic and/or ≥90 mmHg diastolic)
* Chronic use of any prescribed or over the counter pharmaceuticals (excluding oral contraceptives and contraceptive devices)
* Known allergy to lidocaine
* Regular use of dietary protein and/or amino acid supplements (\>3 times per week)
* Currently involved in a structured progressive resistance training programme (\>3 times per week)
* A personal or family history of thrombosis (clots), epilepsy, seizures, or schizophrenia.
* Any previous motor disorders or disorders in muscle and/or lipid metabolism
* Presence of an ulcer in the stomach or gut and/or strong history of indigestion
* Known severe kidney problems
* Pregnant or breastfeeding
* Unable to give consent