Assessing Administration of pBI-11 Via Electroporation for the Treatment of Patients With HPV16/18+

Inclusion Criteria: * Negative for Intraepithelial Lesions (NEIL), Atypical Squamous Cells of Undetermined Significance (ASC-US), or Low-grade Squamous Intraepithelial Lesion (LSIL) determined by cervical cytology AND * HPV16 and/or 18+ by Roche Cobas 4800, Roche Linear Array HPV Genotyping test, or other FDA-approved HPV genotyping test (Co-infections with HPV types other than HPV16/18 are permissible). * Age ≥ 18 years * Baseline Eastern Cooperative Oncology Group performance status of 0 or 1 at the time of enrollment. * Patients must have adequate organ function at the time of enrollment as defined by the following parameters: * White blood cell count ≥ 3,000 cells/uL * Absolute lymphocyte number ≥ 500 cells/uL * Absolute neutrophil count ≥ 1,500 cells/uL * Platelets ≥ 90,000 cells/uL * Hemoglobulin ≥ 9 g/dL * Total bilirubin \< 3 X the institutional limit of normal * Aspartate Aminotransferase (AST) and Alanine Aminotransferase(ALT) \< 3 X the institutional limit of normal * Creatinine \< 2.5 X the institutional limit of normal * Women of child-bearing potential must agree to use long acting contraception (e.g. tubal ligation, intrauterine device or hormonal implant) or two forms of contraception (e.g. barrier method, oral contraceptives) prior to study entry and for 3 months after final vaccination. * Ability to understand and the willingness to sign a written informed consent document. * Able to adhere to the study visit schedule and other protocol requirements. Exc…