Small Intestinal Submucosa Graft for Repair of Anterior Urethral Strictures (NCT06192654) | Clinical Trial Compass
UnknownNot Applicable
Small Intestinal Submucosa Graft for Repair of Anterior Urethral Strictures
China10 participantsStarted 2023-11-10
Plain-language summary
The field of research for this study is tissue engineering and the utilization of a small intestinal submucosa graft as a substitute biomaterial for conventional buccal mucosa in substitution urethroplasty of anterior urethral strictures.
Who can participate
Age range
18 Years
Sex
MALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients signed informed consent form
* Patients with a single, longer than 2.0 cm and shorter than or equal to 7.0 cm anterior urethral stricture
* Patients undergoing substitution urethroplasty for urethral stricture.
Exclusion Criteria:
* Patients without surgical indication
* Subtotal and total urethral strictures
* Radiation therapy to the abdomen or pelvis
* Lichen sclerosis related strictures
* Patients with previous hypospadias repair
* Neurogenic urinary tract disorders
* Mental disorders
* Patients with a known biologic sensitivity or a cultural aversion to the use of porcine materials.
* Patients with severe dysfunction of heart, lung, liver, kidney and other important organs , endocrine system and blood system.
* Patient with malignant tumor
* Patient who cannot be regularly examined due to any circumstances
* Any clinical state which does not ensure the safe implementation of study procedure (investigator's view)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.