Small Intestinal Submucosa Graft for Repair of Anterior Urethral Strictures (NCT06192654) | Clinical Trial Compass
UnknownNot Applicable
Small Intestinal Submucosa Graft for Repair of Anterior Urethral Strictures
China10 participantsStarted 2023-11-10
Plain-language summary
The field of research for this study is tissue engineering and the utilization of a small intestinal submucosa graft as a substitute biomaterial for conventional buccal mucosa in substitution urethroplasty of anterior urethral strictures.
Who can participate
Age range18 Years
SexMALE
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Inclusion Criteria:
* Patients signed informed consent form
* Patients with a single, longer than 2.0 cm and shorter than or equal to 7.0 cm anterior urethral stricture
* Patients undergoing substitution urethroplasty for urethral stricture.
Exclusion Criteria:
* Patients without surgical indication
* Subtotal and total urethral strictures
* Radiation therapy to the abdomen or pelvis
* Lichen sclerosis related strictures
* Patients with previous hypospadias repair
* Neurogenic urinary tract disorders
* Mental disorders
* Patients with a known biologic sensitivity or a cultural aversion to the use of porcine materials.
* Patients with severe dysfunction of heart, lung, liver, kidney and other important organs , endocrine system and blood system.
* Patient with malignant tumor
* Patient who cannot be regularly examined due to any circumstances
* Any clinical state which does not ensure the safe implementation of study procedure (investigator's view)