UnknownEarly Phase 1

Histopathological, Biochemical And Electrophysiological Evaluation Of Single Or Combined Use Of Diode Laser/Steroid Treatment On Facial Nerve Injury

Turkey (Türkiye)35 participantsStarted 2021-01-01

Plain-language summary

The objective of the study will be to investigate the effect of low-level diode laser therapy (LLLT) and steroid on facial nerve injury. Thirty five male Wistar rat will randomly be divided into five groups: healthy control (HCG); damage control (DC); laser (LG); steroid (SG); and combined laser and steroid group (LSG). Right facial nerve electromyography (EMG) data will record after facial nerve damage done and before sacrification at 4th week.The results will be evaluated histopathologically, electrophysiologically and biochemically.

Who can participate

Age range4 Months – 6 Months

SexMALE

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Inclusion criteria

✓Thirty-five male Sprague-Dawley rats weighing 200-300 g will be included the study

Exclusion criteria

✕Rats that are older than 6 months and are not healthy and have impaired facial motor functions will be excluded from the study.

What they're measuring

Electromyographic Analysis

Timeframe: 1 month

Trial details

NCT IDNCT06185426

SponsorRecep Tayyip Erdogan University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-06-01

View on ClinicalTrials.gov More Nerve Injury trials