Low vs Standard Local Anesthetics Boluses for Continuous Adductor Canal Block in Total Knee Arthr… (NCT06179628) | Clinical Trial Compass
CompletedNot Applicable
Low vs Standard Local Anesthetics Boluses for Continuous Adductor Canal Block in Total Knee Arthroplasty
Thailand140 participantsStarted 2023-12-09
Plain-language summary
To investigate the efficacy of two different regimens of local anesthetic boluses for continuous adductor canal block under ultrasound-guidance in total knee arthroplasty at King Chulalongkorn Memorial Hospital.
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients undergoing TKA aged more than 18 years
* Patients with American Society of Anesthesiologists (ASA) class 1-3
* Patients with body weight index (BMI) 18-40 kg/m2
Exclusion Criteria
* Patient refusal to participate
* Patients with known allergic to medications used in the research protocol
* Patients with contraindications to neuraxial or regional anesthesia, including existing neuropathy or neurological deficits involving the lower extremities, coagulopathy or bleeding diathesis and local skin infections
* Patients with contraindications to NSAIDs such as history of coronary artery bypass graft surgery, congestive heart failure, stroke, gastrointestinal bleedings or ulceration, asthma, hepatic and renal disease, abnormal coagulation, or pregnancy
* Patients with chronic opioid use (opioids have been used daily or almost daily for more than three months or sixty milligrams or more of morphine has been used daily for more than one month) or diagnosed with neuropathic pain
* Patients that are unable to perform preoperative Quantitative sensory testing.
What they're measuring
1
Average knee pain score assessed by Numerical rating scale (NRS)
Timeframe: 6 hours after surgery
2
Average knee pain score assessed by Numerical rating scale (NRS)