Personalized Prospective Study Evaluation of the Efficacy and Safety of Noninvasive Neuromodulati… (NCT06176456) | Clinical Trial Compass
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Personalized Prospective Study Evaluation of the Efficacy and Safety of Noninvasive Neuromodulation of TMS in Subjects With Catatonia
Russia60 participantsStarted 2023-11-01
Plain-language summary
Evaluation effectiveness and safety of TMS in subjects with catatonia
Who can participate
Age range18 Years – 35 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Verified diagnosis of schizophrenic or affective spectrum (schizophrenia, schizoaffective disorder, bipolar disorder, major depressive disorder)
Patient's ability (possibly accompanied by caregivers) to undergo diagnostic and therapeutic procedures;
The presence of residual catatonia in the form of such psychomotor anomalies as:
* disorganisation of thinking with speech disturbance with verbigerations and/or sperrungs
* hypo- and hyperkinetic psychomotor phenomena;
* substupor without disturbance of consciousness;
* elective mutism;
* echo phenomena (echolalia and/or echopraxia);
* phenomena of "wax flexibility"
* speech and behavioral stereotypy
* pathetic exaltation phenomena
* the phenomenon of irritative asthenia
* dysuric phenomena (monotonous activity and rigidity of affect)
Exclusion Criteria:
* patient's refusal to participate in the study
* acute hallucinatory-delusional symptoms
* suicide risk
* a patient taking prohibited therapy products
* neuroleptic complications of antipsychotic therapy
* irritative asthenia
* dysuric phenomena by the type of monotonous activity and rigidity of affect
What they're measuring
1
The rate of onset of the primary response
Timeframe: 6 months
2
The number of patients with a positive effect of therapy
Timeframe: 6 months
3
The number of patient with the improvement
Timeframe: 6 months
Trial details
NCT IDNCT06176456
SponsorMoscow Psychiatric Hospital No. 1 Named after N.A. Alexeev