Active — Not RecruitingNot Applicable

Cyclic Versus Continuous Sacral Neuromodulation for LUTS

United States50 participantsStarted 2024-04-15

Plain-language summary

This will be a prospective, randomized-controlled multi-site trial comparing cyclic versus continuous sacral neuromodulation (SNM) for OAB.

Who can participate

Age range18 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients 18 years of age or older * Female * English Speaking * Diagnosis of urinary urge incontinence or overactive bladder * Meet criteria for and are planning permanent SNM (ie. successful stage I or office PNE trial of SNM with 50% or more reduction in UUI episodes) * Willing and able to complete all study related items Exclusion Criteria: * Patients less than 18 years of age * Unable to provide consent * Non-English speaking * Relevant neurologic diseases (multiple sclerosis, Parkinson Disease, myasthenia gravis, - - - Charcot-Marie-Tooth disease, complete spinal cord injury) * Current or prior bladder malignancy

What they're measuring

Change in ICIQ-OAB-QoL score

Timeframe: Baseline, 12 months post-operatively

Trial details

NCT IDNCT06170450

SponsorUniversity Hospitals Cleveland Medical Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-05

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