Effect of a Vegetarian Meal on the Physiology of Insulin Response in Patients With Type 2 Diabetes Mellitus and Obesity

Inclusion Criteria: * Age 18-70 years * Diagnosis of T2DM * In treatment with diet alone or single oral drug metformin * BMI ≥ 30 * HbA1c between 6.0 and 9.0% (42-75 mmol/mol) * Signature of the informed consent Exclusion Criteria: * History of acute/chronic pancreatitis * Pancreatic cancer * Pancreatic surgery * Renal failure (any stage) * Liver cirrhosis * Thyroid disorders (hypothyroidism, hyperthyroidism) * Patients with weight loss in the last 3 months equal to or greater than 5% of body weight * Patients on therapy other than metformin monotherapy (insulin, glucagon-like peptide agonists, sulphonylureas, glitazones, dipeptidyl peptidase inhibitors, SGLT2 inhibitors). * Pregnant or breastfeeding women * History of severe allergic reaction to any food (anaphylaxis)