This study will investigate the feasibility and effects of a smartphone-based mindfulness training program vs. usual care in a sample of stressed midlife and older adults at risk for cardiovascular disease. 105 participants will be randomly assigned to complete a four-week mindfulness training intervention, which involves 28 audio-guided lessons and practice prompts delivered 3x daily, or to continue with their regular routines. Data will be collected at baseline, post-intervention, and three-month follow-up. The study will involve seven laboratory visits, which will include assessments and training on daily life monitoring and intervention procedures. Data assessing subjective and physiological stress reactivity in daily life will be collected for 3 days at pre-intervention, post-intervention, and 3-month follow-up. Passive sensor data will be continuously collected from participants' smartphones and wearable devices to develop models that predict daily life stress. Data will be used to evaluate feasibility of the intervention and assessments in a sample at risk for cardiovascular disease and to test effects of mindfulness training on subjective and physiological stress reactivity.
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Change in Task Strain from pre-intervention to post-intervention
Timeframe: Change in Task Strain assessed for 3 days at pre-intervention and post-intervention (an average of 5 weeks)
Change in Task Strain from pre-intervention to 3-month follow-up
Timeframe: Change in Task Strain assessed for 3 days at pre-intervention and three-month follow-up (an average of 18 weeks)
Change In Systolic Blood Pressure Response to Momentary Psychosocial Stress from pre-intervention to post-intervention
Timeframe: Change in Systolic Blood Pressure Response to Momentary Psychosocial Stress assessed for 3 days at pre-intervention and post-intervention (an average of 5 weeks)
Change In Systolic Blood Pressure Response to Momentary Psychosocial Stress from pre-intervention to 3-month follow-up
Timeframe: Change in Systolic Blood Pressure Response to Momentary Psychosocial Stress assessed for 3 days at pre-intervention and three-month follow-up (an average of 18 weeks)
Change in Social Conflict from pre-intervention to post-intervention
Timeframe: Change in Social Conflict assessed for 3 days at pre-intervention and post-intervention (an average of 5 weeks)
Change in Social Conflict from pre-intervention to 3-month follow-up
Timeframe: Change in Social Conflict assessed for 3 days at pre-intervention and three-month follow-up (an average of 18 weeks)
Change in Systolic Blood Pressure Response to Social Conflict from pre-intervention to post-intervention
Timeframe: Change in Systolic Blood Pressure Response to Social Conflict assessed for 3 days at pre-intervention and post-intervention (an average of 5 weeks)
Change in Systolic Blood Pressure Response to Social Conflict from pre-intervention to 3-month follow-up
Timeframe: Change in Systolic Blood Pressure Response to Social Conflict assessed for 3 days at pre-intervention and three-month follow-up (an average of 18 weeks)
Feasibility of recruitment
Timeframe: Assessed at enrollment
Feasibility of retention
Timeframe: Assessed across the entire 5-month study period
Feasibility of adherence
Timeframe: Assessed across the entire 5-month study period
Acceptability: Treatment Expectancies
Timeframe: Treatment Expectancies assessed among participants randomized to the mindfulness condition at pre-intervention, post-intervention (average of 5 weeks), and 3-month follow-up (average of 19 weeks)
Feasibility of safe implementation: Side Effects
Timeframe: Adverse effects assessed among participants randomized to the mindfulness condition at pre-intervention, post-intervention (average of 6 weeks), and 3-month follow-up (average of 20 weeks)
Acceptability: Study Burden
Timeframe: Study Burden assessed at post-intervention and 3-month follow-up