Barley Beta-glucan, Glycemic Control, and Appetite
United States16 participantsStarted 2019-10-01
Plain-language summary
Novel barley varieties high in the soluble fiber β-glucan have the capacity to improve population health through improving glycemic control. Sweetened and unsweetened wholegrain barley foods were tested in a randomized, controlled, crossover human clinical trial to assess impact on postprandial appetite and food intake.
Who can participate
Age range18 Years – 50 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* 18-50 years of age
* Body Mass Index (BMI) values of 18.5-40.0 kg/m2
* Normal fasting blood glucose (\<100 mg/dL)
Exclusion Criteria:
* Use of medications known to be associated with weight change (e.g., beta-blockers)
* Use of steroid pills or shots such as prednisone or cortisone
* Use of nicotine
* Weight change of ten or more pounds in the last three months
* Major daily variation in physical activity (e.g., athletes in training)
* History of extensive small bowel surgery or surgery to treat obesity
* History of heart attack, stroke, or bypass
* History of cancer within the last five years (exception: non-melanoma skin cancer)
* Recent or current medical diagnosis or medical treatment that would alter appetite, energy needs, satiety, and/or could impact the results of the trial
* Medical diagnoses of diabetes, cardiovascular disease, high levels of blood lipids, asthma, cold, and flu (exception: hypertension, if treated with medication prescribed more than three months prior to the screening activity)
* Fear of blood or needles
* Dietary restrictions that would interfere with consuming test foods (e.g., gluten intolerance, vegan, corn syrup allergy)
* Following a weight modification diet
* Sensitive to food textures present in the test foods
* Following personal schedules that would not permit attendance at all scheduled testing sessions
* Unable to comprehend the nature of the trial or instructions
* Unable to understand English sufficiently to c…