A Pilot Study For Patients Receiving Radiation Therapy for Liver Cancer

Inclusion Criteria: * Patient has the psychological ability and general health needed to provide informed consent, completion of study requirements, and required follow-up * Patient provides study-specific informed consent prior to study entry * All primary histologies (Hepatocellular carcinoma or Cholangiocarcinoma) as well as hepatic metastases are eligible * Prior history of radiation therapy (external beam or radioembolization) is allowed, with no limit to the number of prior courses of radiation therapy * Any number of lesions (with no size limit) of pathologically documented (histologically or cytologically) or radiographically proven tumor/metastasis that are being targeted * Prior history of chemotherapy, immunotherapy, or targeted biological therapy is allowed * Concurrent enrollment on other prospective registry or treatment intention trials is allowed Exclusion Criteria: * Pregnant or breast-feeding females * Subjects with history of claustrophobia impacting ability to perform MRI during the study * Subjects who fulfill any of the contraindications for MRI; examples include any ferromagnetic material, any metallic shrapnel or fragments or implanted electronic devices contained within the body or metal-containing tattoos * Unable to participate in MR assessments due to physical limitations of equipment tolerances (MRI bore size and/or weight limit) * Any person unable to lie still within the environment of the MRI scanner or maintain a breath hold for the require…