The goal of this interventional study is to evaluate the impact of Hospital Clowns (HCs) intervention, besides to hospital hosting conditions, in the well-being of adult female patients during ambulatory chemotherapy. The main question\[s\] it aims to answer are: * Do the short-term HCs interventions during ambulatory chemotherapy may increase well-being of adult cancer patients in comparison to the hospital hosting conditions? * Do the short-term HCs interventions, besides the hospital hosting conditions, have effects on well-being biomarkers in association with psychological outcomes? Participants self-collect a sample of saliva followed by psychological assessment, at a first time-point (basal) and at a final time-point (\~after 90 minutes of basal) (pre- and post-test), during the chemotherapy treatment session. Researchers have compared an HCs intervention plus hosting conditions - experimental group, EG, and hosting conditions only - control group, CG, by the repeated measures of pre- and post-test of biomarkers in saliva and the psychological functioning evaluations, to see the degree of the impact of HCs intervention in the well-being of the patients in comparison with normal hosting conditions. Each HCs intervention lasts around 15 minutes, and it is performed in the middle of the procedure between pre- and post-test.
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Oxytocin levels (saliva)
Timeframe: Basal and after ~ 90 minutes, during the chemotherapy treatment session
Cortisol levels (saliva)
Timeframe: Basal and after ~ 90 minutes, during the chemotherapy treatment session
Serotonin levels (saliva)
Timeframe: Basal and after ~ 90 minutes, during the chemotherapy treatment session
ATP levels (saliva)
Timeframe: Basal and after ~ 90 minutes, during the chemotherapy treatment session