RecruitingNot Applicable

2D/3D Imaging to Analyze the Regeneration Rate of Autologous Bone

Taiwan48 participantsStarted 2024-06-06

Plain-language summary

Place a collagen plug (collagen plug) in the lower 2/3 to 1/2 of your tooth extraction site while giving you Vit. The extracted teeth are made into autogenous tooth root thin slices and covered in your tooth extraction cavity, and the skin flap raised by your flap surgery is used to cover the autologous tooth root cover to help the autologous tooth roots stabilize and heal the wound, which is different from traditional surgery. The difference in treatment lies in the local use of autogenous tooth root thin slices and Vit.D3. Collagen plug and Vit.D3 are already qualified medical materials and drugs on the market. However, there is no precedent for making thin autologous tooth root slices. will be a trial of a new medical technology that has not yet been used

Who can participate

Age range20 Years – 70 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Willing to sign written subject consent
✓. The tooth extraction socket is located in the anterior and posterior areas of the upper and lower jaws.
✓. The area of the extraction socket (bone defect) in the mouth will need to be treated with artificial dental implants in the future.
✓. The patient does not have systemic diseases (such as patients with hypertension, osteoporosis, bone-related diseases, kidney disease, thyroid and parathyroid diseases, etc.).

Exclusion criteria

✕. Patients with potentially weakened healing abilities such as cancer, diabetes, bone infection, tuberculosis, anemia due to heme abnormalities or congenital immune deficiency, cellulitis, acute periodontal cyst, severe cusp disease (cyst size) \>2mm2) or patients with dental and jaw lesions.
✕. Women who are pregnant or breastfeeding.
✕. Exclude heavy smokers or betel nut chewers who smoke more than one pack of cigarettes per day.
✕. The bone defect in the extraction socket is severe and requires other bone regeneration surgeries (GBR), otherwise it will not be possible to have enough volume to provide artificial dental implants in the future.

What they're measuring

3D computed tomography data

Timeframe: At the 0th week and 12th~16th week of the experiment

periapical X-ray

Timeframe: 16 weeks after tooth extraction (before dental implants or other treatments)

Intraoral scanner measurement data

Timeframe: At the 0th week and 12th~16th week of the experiment

RFA measures implant stability (ISQ)

Timeframe: At the 16th~24th week of the experiment

Trial details

NCT IDNCT06141239

SponsorChang Gung Memorial Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-05-31

Contact for this trial

Hsiang Hsi Hong

+886975365989 f1214@adm.cgmh.org.tw

View on ClinicalTrials.gov More Alveolar Ridge Preservation trials

Plain-language summary

Who can participate

Age range20 Years – 70 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Willing to sign written subject consent
✓. The tooth extraction socket is located in the anterior and posterior areas of the upper and lower jaws.
✓. The area of the extraction socket (bone defect) in the mouth will need to be treated with artificial dental implants in the future.
✓. The patient does not have systemic diseases (such as patients with hypertension, osteoporosis, bone-related diseases, kidney disease, thyroid and parathyroid diseases, etc.).

Exclusion criteria

✕. Patients with potentially weakened healing abilities such as cancer, diabetes, bone infection, tuberculosis, anemia due to heme abnormalities or congenital immune deficiency, cellulitis, acute periodontal cyst, severe cusp disease (cyst size) \>2mm2) or patients with dental and jaw lesions.
✕. Women who are pregnant or breastfeeding.
✕. Exclude heavy smokers or betel nut chewers who smoke more than one pack of cigarettes per day.
✕. The bone defect in the extraction socket is severe and requires other bone regeneration surgeries (GBR), otherwise it will not be possible to have enough volume to provide artificial dental implants in the future.

What they're measuring

3D computed tomography data

Timeframe: At the 0th week and 12th~16th week of the experiment

periapical X-ray

Timeframe: 16 weeks after tooth extraction (before dental implants or other treatments)

Intraoral scanner measurement data

Timeframe: At the 0th week and 12th~16th week of the experiment

RFA measures implant stability (ISQ)

Timeframe: At the 16th~24th week of the experiment