RecruitingNot Applicable

GCS Survey: "GHB IN CHEMICAL SUBMISSION: MYTH OR REALITY?"

France200 participantsStarted 2024-03-20

Plain-language summary

According to the media, GHB is the main substance used for chemical submission. The national survey conducted by the Addictovigilance centre of Paris on drug-facilitated assaults shows that GHB is used, but only in a very small proportion of cases. However, the short detection times for this substance point to its possible under-detection (06-09h in blood, 10-12h in urine). A pilot research protocol in Ile de France focusing on capillary analysis is therefore being proposed to volunteer victims to overcome this bias and answer this question: is the massive use of GHB in chemical submission a myth or a reality?

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Victims over the age of majority (≥ 18 years) on the day of the alleged events * With a medical history leading to the suspicion of chemical submission: * Presence of evocative clinical signs (amnesia and/or behavioural disorders and/or neurological disorders and/or other somatic disorders, etc.) AND * In the presence of potential criminal acts (suspected or proven assault or attempted assault). * French speaking * Having been informed of the search Exclusion Criteria: * \- Victims who were minors (\<18 years) on the day of the alleged events. * Victims who usually use GHB/GBL recreationally. * Suspecting administration of a harmful substance with no crime or offence committed at the time and no attempted assault * Victims of needle spiking * Victims with very short hair (\<3 cm), bald or shaven heads * Victims who have exceeded the maximum time limit for taking a hair sample (6 months after the event) * Do not speak French * Oppose to participating in the study * Victims presenting a psychotic or cognitive syndrome likely to impair judgement Victims placed under guardianship or legal protection (article L11-22-2 CSP)

What they're measuring

Evidence of exogenous GHB intake without the knowledge of the victims through hair analysis.

Timeframe: Samples taken between 2 and 6 months after the presumed events: GHB analysis in the hair can no longer be interpreted after 6 months due to the hydrosoluble nature of GHB and repetitive hair washing.

Trial details

NCT IDNCT06137599

SponsorAssistance Publique - Hôpitaux de Paris

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-03-20

Contact for this trial

Leïla CHAOUACHI, PharmD

01 40 05 42 70 Leila.chaouachi@aphp.fr

View on ClinicalTrials.gov More CHEMICAL SUBMISSION trials