Study to Assess Colonic Microbiota Changes in Response to Energy Drink Consumption (NCT06137248) | Clinical Trial Compass
CompletedPhase 2
Study to Assess Colonic Microbiota Changes in Response to Energy Drink Consumption
United States76 participantsStarted 2024-02-28
Plain-language summary
This study will investigate whether short-term daily energy drink consumption results in an increase in hydrogen sulfide-producing bacteria in adults 18-40 years old.
Who can participate
Age range18 Years – 40 Years
SexALL
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Inclusion Criteria:
* Adults ≥ 18 years of age AND ≤ 40 years of age
* Written informed consent obtained from the subject and the subject agrees to comply with all the study-related procedures
* Subject willing to complete/comply with study required specimen and survey assessments
* Current energy drink consumption of ≤2 energy drinks weekly
* Written informed consent obtained from the subject to participate in two companion biobanks: 1) Dr. Thomas George's Tumor and Biospecimen Sample Biobank and 2) Dr. Ryan Thomas's Microbiorepository for future research.
Exclusion Criteria:
* Personal history of colorectal cancer (CRC)
* Inflammatory Bowel Disease (IBD)
* Chronic diarrhea or other chronic gastrointestinal (GI) problems felt to interfere with study conduct per the PI
* Regular (daily) intake of probiotics
* Oral or IV antibiotic use within the past 28 days (prior to intervention start date)
* Known intolerance of or sensitivity to caffeine
* Prisoners or subjects who are involuntarily incarcerated, or subjects who are compulsorily detained for treatment of either a psychiatric or physical illness.
* Known pregnancy at the time of enrollment
What they're measuring
1
Change in the hydrogen sulfide-metabolizing species of bacteria