The present study aimed to assess the effect of non-surgical periodontal treatment on serum and salivary chemerin, fetuin-A, IL-34 and IL-13 levels in periodontitis with and without diabetes mellitus (DM) type 2. 22 non-periodontitis, 22 non-periodontitis with DM, 22 Stage III/IV Grade C periodontitis, 22 tage III/IV Grade C periodontitis with well-controlled DM and 22 tage III/IV Grade C periodontitis with poorly-controlled DM patients were enrolled. At baseline, serum and saliva samples were collected, and the whole mouth clinical periodontal parameters were recorded from all subjects. Periodontitis patients received non-surgical periodontal therapy. Clinical parameters were re-measured, and samples were re-collected 1 and 3 months after therapy from periodontitis patients. Serum and salivary protein levels were analyzed by ELISA. Data were analyzed using appropriate statistical tests.
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salivary chemerin level (ng/ml)
Timeframe: baseline to 3 months after non-surgical
salivary fetuin-A level (ng/ml)
Timeframe: baseline to 3 months after non-surgical
salivary IL-34 level (pg/ml)
Timeframe: baseline to 3 months after non-surgical
salivary IL-13 level (pg/ml)
Timeframe: baseline to 3 months after non-surgical