UnknownNot Applicable

Modifying Working Memory With Brain Stimulation

Netherlands9 participantsStarted 2023-11-01

Plain-language summary

The investigators want to investigate the effect of rTMS on working memory measured by the N-back task. This is a single case experimental design, ABAB.

Who can participate

Age range

18 Years – 75 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Had a cardiac arrest between 3 months and 5 years prior to the experiment session. * Scores lower than the general population (corrected for age, education, and sex) on at least one of the cognitive tests ( SD \< -1 on the Stroop, digit span, or TMT). * Age 18 up to and including 75. * Proficient in Dutch or English to understand the instructions for the N-back task. * Has sufficient understanding to perform the N-back task. * Written informed consent Exclusion Criteria: * Has a pacemaker or ICD (implantable cardioverter-defibrillator) * A history or a family member with a history of seizures / epilepsy (asked on the phone and checked on the first appointment). * Metal implants in or near the head. * Pregnancy * Any other neurological disorder impending working memory performance besides the OHCA.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Accuracy on the N-back task

Timeframe: 1 measurements every 2 minutes for 8 - 10 minutes after each N-back task (4 times in total)

Trial details

NCT IDNCT06119620

SponsorMaastricht University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-08-01

Contact for this trial

Pauline V van Gils, MSc

+31 (0)43 38 84095 c.vangils@maastrichtuniversity.nl

View on ClinicalTrials.gov More Cardiac Arrest trials

Who can participate

Age range

18 Years – 75 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.