Transcranial Magnetic Stimulation in Patients With Depression and Non-suicidal Self-injury

Inclusion Criteria: * Current diagnosis of major depressive disorder by the operational criteria of DSM-5 and non-suicidal self-injury behavior, defined by "engagement in and intentionally self-inflicted harm to the surface of one's body, likely resulting in bleeding, bruising, or pain (e.g., cutting, burning, puncturing, hitting, excessive rubbing), with the expectation that the injury will only lead to minor or moderate physical harm (i.e., no suicidal intent)". (at least one episode in the past year); * Depression severity score ≥17 points (moderate depression criteria) on the 17-item Hamilton Depression Rating Scale (HAM-D-17); * Currently receiving psychiatric treatment and/or engaged in psychotherapy with a minimum biweekly frequency; * Consent to voluntary participation in the study, confirmed by signing the Informed Consent Form; * Expressed willingness to comply with all study procedures, including imaging examinations and blood tests, with availability during the study, and to communicate with the study team regarding adverse events and other clinically important information; * Commitment to access continuous psychiatric care before and after study completion; * In good general health, as evidenced by medical history. Exclusion Criteria: * Participants who present pre-established contraindications for undergoing EMT, based on positive responses in the "TMS Adult Safety Screen (TASS)" questionnaire, such as: cochlear implants, brain stimulators (DBS), electrode im…