Nexpowder to Prevent Delayed Bleeding After Endoscopic Resection

Inclusion Criteria: * Age: ≥18 year of age at the time of informed consent, * Patients must have given written informed consent, * Subjects with documented lesions with indication of upper or lower endoscopic removal by ESD or EMR with high risk of delayed bleeding (+/-16%), namely: * All patients under anticoagulation (vitamin K antagonist, direct anticoagulant, non-fractionated heparin or low molecular weight heparin) or anti-aggregating (P2Y12 receptor antagonists), * Patients without anticoagulation or anti-aggregating with indication of duodenal EMR or ESD (if duodenal cold snare EMR: only under anticoagulant or P2Y12 receptor antagonist), * Resection field of ESD or EMR is ≥ 20mm (same size restriction in case of endoscopic papillectomy). Exclusion Criteria: * Resection bed \<20mm, * Subject currently enrolled in another interventional confounding research (no contra-indication for image or blood collection in another protocol), * Incapacitated subjects, pregnant or lactating women.