A Pilot Study to Evidence Improved Cranial Flap Fixation With a Bioresorbable Bone Adhesive

Inclusion Criteria: * Subjects or representatives must have voluntarily signed the informed consent form before any study related procedures. * Subjects can be any gender, but be between (and including) 18 and 75 years of age * Subject is scheduled for a cranial procedure in the supratentorial location. * Subject requires a procedure involving a Class I/clean wound (uninfected surgical wound in which no inflammation was encountered). * Subject, and/or subject's family are able and willing to provide informed consent and HIPAA authorization. * Subject is able and willing to meet all study requirements, including attending all post-index procedure assessment visits and radiological tests. Intra-Operative Inclusion Criteria: * Width of craniotomy kerf line \< 3mm for more than 75% of the bone flap border Exclusion Criteria: * Subject requires a procedure involving a translabyrinthine, transsphenoidal, transoral approach, or any procedure that penetrates the air sinus or mastoid air cells. Note: Superficial penetration of mastoid air cells is not an exclusion if cells were appropriately sealed (e.g., bone wax). * Subject has clinically significant hydrocephalus or clinical evidence of altered CSF dynamics. * Subject has undergone a previous, open intracranial neurosurgical procedure in the same anatomical location. (Note: stereotactic biopsy was not exclusionary). * Subject requires a craniectomy (the bone flap is not replaced during the current surgery). * Subject had radia…