Investigating Implant Surface Effect on Osseointegration: NGA vs. ModSLA (NCT06086873) | Clinical Trial Compass
RecruitingNot Applicable
Investigating Implant Surface Effect on Osseointegration: NGA vs. ModSLA
United Kingdom39 participantsStarted 2023-09-05
Plain-language summary
This study aims to characterise the stability of crestal bone levels one year after loading, the associated aesthetic outcomes, immunological response, prosthodontic outcomes as well as overall patient reported outcome measures for modSLA (SLActive, Institut Straumann AG, Switzerland) and NGA (TiUltraNP, Nobel Biocare AG, Switzerland) dental implants.
Who can participate
Age range18 Years
SexALL
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Inclusion Criteria:
* Age: over 18 years old,
* Gender: male and female.
* Patient must be able and willing to follow study procedures and instructions and have capacity to provide informed consent.
* Patient must require tooth extraction of a maxillary first premolar or single-rooted anterior tooth as the result of caries, endodontic failure or trauma
* The extraction site must have adjacent teeth present.
* Adjacent teeth with no evidence of interdental bone loss
Exclusion Criteria:
* Systemic disease that can interfere with dental implant therapy (e.g. uncontrolled diabetes)
* 2 adjacent teeth requiring extraction
* Greater than one wall of the socket missing - assessed at time of extraction
* Any contraindications for oral surgical procedures
* Any known systemic disease affecting bone metabolism (e.g. Cushing's syndrome, Crohn's disease, rheumatoid arthritis, osteoporosis, diabetes type I and uncontrolled diabetes type II), systemic infections or recent surgical procedures within 30 days of study initiation;
* Chronic treatment (i.e., 2 weeks or more) with any medication known to affect oral status (e.g., phenytoin, dihydropyridine, calcium antagonists and cyclosporine) or bone metabolism (e.g. bisphosphonates, hormone replacement therapy, immunosuppressants) within 1 month before baseline visit;
* HIV or viral hepatitis;
* Physical handicaps that would interfere with the ability to perform adequate oral hygiene;
* History of local irradiation therapy in the head-neck…