Fecal Microbiota Transplant for Autobrewery Syndrome

Inclusion Criteria: * 18-70 with documented ABS symptoms for at least one year, including supervised ethanol testing or a positive glucose challenge test in a supervised setting. * Active ABS including at least 3 flares by either serum or breath alcohol levels in the past year (blood or breath samples) * Subject's microbiome produces alcohol ex vivo in bioreactor (Schnabl laboratory) * Willing and able to travel to Boston for in person assessment (modest reimbursement available) * Willing to stop antifungals, and any other complimentary therapies for ABS, if taking * Medically able to withstand clean out. If participants are over 60, the subject must have previously tolerated a prior colonoscopic "prep" as part of prior routine care. * Local physician contact available Exclusion Criteria: * Unwilling/unable to swallow large capsules (e.g.esophageal stricture or hiatal hernia) * Delayed gastric emptying syndrome * Known chronic aspiration, or chronic nausea/vomiting * Pregnant (pregnancy testing will be performed in women of childbearing potential; women over 52 with no menses for 12 months will not require testing) * Patients with an acute active illness or acute exacerbation of underlying comorbid condition. * Patients on unstable, or increasing immunosuppressive agents including high dose corticosteroids(40 mg prednisone daily or more), calcineurin inhibitors, escalating immunosuppression for organ rejection, active chemotherapy with expected neutropenia, current or neut…