Antiseizure Medication in Seizure Networks at Early Acute Brain Injury

Inclusion Criteria: * Currently ICU hospitalized. * Suppression of consciousness related to a neurological injury by medical chart review. * Glasgow Coma Scale of less than 13 at enrollment by medical chart review. * Diagnosis of Acute brain injury by traumatic brain injury (TBI), hypoxic-ischemic insult, cardiac arrest, or stroke by medical chart review. * 2 to 90 days from acute brain injury to enrollment time by medical chart review. * Have a surface EEG performed after the current ICU admission * Clinically stable to undergo MRI scan, This stability is defined by care team concept, which should be stated in the medical records. Exclusion Criteria: * Previous medical history of Epilepsy by medical chart review. * Previous medical history of neurological sequels that lead to dependence on care for basic daily activities, by Barthel index score less than 80. * Known allergy/Hypersensitivity or medical contraindications (like porphyria or cardiac arrhythmias) to the treatment protocol options, leaving no potential combination of drugs for the intervention without concerns for adverse events related to known preexistent conditions. * Considered with Brain death by the care team in the medical record, at any time. * Speaking fluently or at their prior reported baseline mental status by medical chart review before the intervention starts. * Contraindications for MRI scan. * Prisoner human subjects by medical chart review. * Confirmed currently pregnant by medical history or b…