Stopped: Sponsor Decision
The purpose of this study is to learn about dacomitinib for the possible treatment of lung cancer which has spread to other parts of the body. This study is seeking participants who: * have lung cancer that has reached at least the brain. * have a type of gene called epidermoid growth factor receptor. A gene is a part of your DNA that has instructions for making things your body needs to work. * have not received any treatment before. All participants in this study will receive dacomitnib 1 time a day. Dacomitinib is a tablet that is taken by mouth at home. They can continue to take dacomitnib until their cancer is no longer responding. The study will look at the experiences of people receiving the study medicine. This will help to see if the study medicine is safe and effective.
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The real-world intracranial overall response rate (rwICORR) at Month 3
Timeframe: 3 months from first dose of dcomitnib
The real-world intracranial overall response rate (rwICORR) at Month 6
Timeframe: 6 months from first dose of dacomitnib
The real-world intracranial overall response rate (rwICORR) at Month 12
Timeframe: 12 months from first dose of dacomitinib
The real-world intracranial clinical benefit rate (rwICBR) at Month 3
Timeframe: 3 months from first dose of dacomitinib
The real-world intracranial clinical benefit rate (rwICBR) at Month 6
Timeframe: 6 months from first dose of dacomitinib
The real-world intracranial clinical benefit rate (rwICBR) at Month 12
Timeframe: 12 months from first dose of dacomitinib
The real-world intracranial time to progression (rwICTTP)
Timeframe: 30 months from first dose of dacomitinib
The real-world systemic overall response rate (rwORR) at Month 3
Timeframe: 3 months from first dose of dacomitinib
The real-world systemic overall response rate (rwORR) at Month 6.
Timeframe: 6 months from first dose of dacomitinib
The real-world systemic overall response rate (rwORR) at Month 12.
Timeframe: 12 months from first dose of dacomitinib
The real-world progression-free survival (rwPFS) during 12 months from index date
Timeframe: 12 months from index date
The real-world overall survival (rwOS) during 12 months from index date
Timeframe: 12 months from index date
The real-world overall survival (rwOS) during 24 months from index date
Timeframe: 24 months from index date