Ultrasound-guided Thyroid Cartilage Plane Block for Awake Intubation
China60 participantsStarted 2023-10-15
Plain-language summary
The goal of this clinical trial is to investigate the clinical effectiveness and safety of superior laryngeal nerve block through surface injection of local anesthetic solution on the thyroid cartilage in patients undergoing general anesthesia with endotracheal intubation. The main questions it aims to answer are the effectiveness of ultrasound-guided Thyroid Cartilage Plane Block for superior laryngeal nerve blockadethe and the safety and ease of performance.
All patients are divided into the Thyroid Cartilage Plane Block Group (T Group) and the Control Group (C Group). Patients in the C Group receive airway surface anesthesia using the fiberoptic bronchoscope-guided local anesthetic spray method throughout the procedure. In the experimental T Group, ultrasound-guided bilateral Thyroid Cartilage Plane Block is performed using the thyroid cartilage as an anatomical landmark. Local anesthetic is injected on the surface of the thyroid cartilage.
Compare the following parameters between the two groups: duration of the blocking procedure, Ramsay Sedation Score, patient coughing upon contact of the fiberoptic bronchoscope with the vocal cords before intubation, comfort score immediately after intubation, and tracheal tube tolerance after successful intubation.
Who can participate
Age range18 Years – 65 Years
SexALL
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Inclusion criteria
✓. Patients scheduled for awake tracheal intubation surgery under general anesthesia.
✓. Patients with difficult airways (e.g., limited cervical spine mobility, full stomach, partial airway obstruction, craniofacial deformities or trauma, micrognathia, mouth opening \<3cm, Mallampati III or IV classification) posing challenges for mask ventilation or intubation.
✓. Age between 18 and 65 years.
✓. Gender is not restricted.
✓. ASA classification of I or II.
Exclusion criteria
✕. Cardiovascular dysfunction or arterial aneurysms.
✕. Mental or neurological disorders or concomitant arterial aneurysms.
✕. Infection at the puncture site.
✕. Allergy to local anesthetics.
✕. Continuous use of antiplatelet or anticoagulant medications preoperatively.
What they're measuring
1
quality of airway anesthesia
Timeframe: Upon intubation
Trial details
NCT IDNCT06065475
SponsorNanjing First Hospital, Nanjing Medical University