CAE for Poorly Adherent Individuals With Schizophrenia (NCT06061952) | Clinical Trial Compass
CompletedNot Applicable
CAE for Poorly Adherent Individuals With Schizophrenia
United States36 participantsStarted 2024-01-16
Plain-language summary
This project aims to evaluate the feasibility, acceptability and preliminary efficacy of remotely delivered CAE among patients with schizophrenia (CAE-S).
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Individuals age 18 and older with schizophrenia as confirmed by the Mini International Psychiatric Inventory (MINI)
* Prescribed an antipsychotic medication for treatment of schizophrenia
* Known to have medication treatment adherence problems as identified by the Tablets Routine Questionnaire (TRQ, 20% or more missed medications in past week or past month)
* Ability to be rated on psychiatric rating scales
* Currently in treatment or scheduled to receive treatment at a Community Mental Health Clinic (CMHC) or other clinical setting able to provide mental health care during and after study participation
* Able to provide written, informed consent to study participation
* Has access to electronic device and internet to complete sessions conducted on videoconferencing platform
Exclusion Criteria:
* Prior or current treatment with clozapine (clozapine therapy includes additional medication-related monitoring and clinical visits that may impact medication adherence)
* Medical condition or illness, which in the opinion of the research psychiatrist, would interfere with the patient's ability to participate in the trial
* Physical dependence on substances (alcohol or illicit drugs) likely to lead to withdrawal reaction during the course of the study in the clinical opinion of the treated research psychiatrist
* Immediate risk of harm to self or others
* Female who is currently pregnant or breastfeeding
What they're measuring
1
Average Number of CAE-S Sessions Attended by Those in the CAE-S Group After 12 Weeks
Timeframe: 12 weeks
2
Percentage of Subjects in the CAE-S Group That Agree or Strongly Agree That the Intervention Was Useful at 12 Weeks
Timeframe: 12 weeks
Trial details
NCT IDNCT06061952
SponsorUniversity Hospitals Cleveland Medical Center