Correction of Hypernatremia by Intravenous Hypotonic Solution Compared to Enteral Water (NCT06061783) | Clinical Trial Compass
UnknownNot Applicable
Correction of Hypernatremia by Intravenous Hypotonic Solution Compared to Enteral Water
178 participantsStarted 2023-11-30
Plain-language summary
Hypernatremia, defined as an elevation of serum sodium \>145 mEq/L, is one of the most common electrolyte disturbances in hospitalized patients and intensive care units.
In this study, the investigator aims, for the first time, to compare two strategies used for the correction of hypernatremia, using intravenous hypotonic solution compared to naso- or orogastric tube enteral water.
Who can participate
Age range
18 Years – 90 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Hospitalized patients with hypernatremia (serum sodium\>145mEq/L).
Exclusion Criteria:
* Age below 18 years
* Pregnant, on dialysis
* Unwilling to participate or without informed consent.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is comparing an IV hypotonic solution to enteral water for correcting high sodium levels — given my specific situation, which of these two approaches does my doctor think would be safer or more practical for me?
2Since this trial has an 'unknown' recruitment status, is it still actively enrolling patients, and would my doctor be able to find out if I could even be considered for it?
3This study doesn't have a traditional phase number, which suggests it may be evaluating a practical treatment question rather than a brand-new drug — does that mean there's already some safety data on both methods, and what does my doctor think the real unknowns are?
4How quickly does my sodium level need to be corrected, and would the demands of participating in a comparison study like this — where my treatment method might be assigned rather than chosen — be appropriate given how urgent my condition is?
5Are there standard-of-care approaches my doctor would already recommend for correcting my hypernatremia, and is there a meaningful reason to consider a trial like this instead of just going with the established treatment?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
The efficiency of intravenous hypotonic solution for the correction of hypernatremia compared with enteral water.
Timeframe: every 12 hours during the first 48hrs of treatment and then every 24 hours for the first 5 days of the study.