CompletedNot Applicable

Stroke and CPAP Outcome Study 3

United States36 participantsStarted 2023-10-01

Plain-language summary

A problem with breathing during sleep, called obstructive sleep apnea (OSA), likely increases the risk of stroke and is common in people who have had a stroke, present in about 2/3 of stroke survivors. There is also evidence that OSA predicts worse outcome after stroke. The question being addressed in the Stroke and CPAP Outcome Study 3 (SCOUTS3) is how to improve use of continuous positive airway pressure (CPAP) therapy to treat OSA when started during intensive stroke rehabilitation.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age 18 years or older * Head CT or brain MRI demonstrating an acute ischemic infarction or intraparenchymal hemorrhage within past 30 days * Person providing consent (patient or legally authorized representative) able to be consented in English or Spanish Exclusion Criteria: * Unable to obtain informed consent from participant or surrogate * Incarcerated * Known pregnancy * Current mechanical ventilation, tracheostomy or supplemental oxygen use \> 4L/min * Current use of positive airway pressure or use within 14 days prior to stroke * History of pneumothorax, bullous emphysema or other serious co-morbid conditions which limit CPAP use * Stroke related to tumors, vascular malformations or subarachnoid hemorrhage * Active use of sedative drugs that can interfere with testing for obstructive sleep apnea (OSA) * Anticipated inpatient rehabilitation length of stay \< 3 nights

What they're measuring

CPAP Adherence

Timeframe: From CPAP initiation after study enrollment and sleep apnea testing to 90 days from CPAP initiation

Trial details

NCT IDNCT06029959

SponsorUniversity of Washington

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-09-30

Results submitted2025-08-30