Stroke and CPAP Outcome Study 3 (NCT06029959) | Clinical Trial Compass
CompletedNot Applicable
Stroke and CPAP Outcome Study 3
United States36 participantsStarted 2023-10-01
Plain-language summary
A problem with breathing during sleep, called obstructive sleep apnea (OSA), likely increases the risk of stroke and is common in people who have had a stroke, present in about 2/3 of stroke survivors. There is also evidence that OSA predicts worse outcome after stroke. The question being addressed in the Stroke and CPAP Outcome Study 3 (SCOUTS3) is how to improve use of continuous positive airway pressure (CPAP) therapy to treat OSA when started during intensive stroke rehabilitation.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age 18 years or older
* Head CT or brain MRI demonstrating an acute ischemic infarction or intraparenchymal hemorrhage within past 30 days
* Person providing consent (patient or legally authorized representative) able to be consented in English or Spanish
Exclusion Criteria:
* Unable to obtain informed consent from participant or surrogate
* Incarcerated
* Known pregnancy
* Current mechanical ventilation, tracheostomy or supplemental oxygen use \> 4L/min
* Current use of positive airway pressure or use within 14 days prior to stroke
* History of pneumothorax, bullous emphysema or other serious co-morbid conditions which limit CPAP use
* Stroke related to tumors, vascular malformations or subarachnoid hemorrhage
* Active use of sedative drugs that can interfere with testing for obstructive sleep apnea (OSA)
* Anticipated inpatient rehabilitation length of stay \< 3 nights
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
CPAP Adherence
Timeframe: From CPAP initiation after study enrollment and sleep apnea testing to 90 days from CPAP initiation