UnknownNot Applicable

Assessing the Role of Mitochondrial Dysfunction in Primary Progressive Multiple Sclerosis

Italy140 participantsStarted 2021-09-20

Plain-language summary

The purpose of this project is to study genetic determinants of mitochondrial impairment in primary progressive multiple sclerosis. Specific aims are: 1) identify mitochondrial-related pathways, inherited and somatic mitochondrial DNA mutations associated to primary progressive multiple sclerosis, 2) functionally assess the identified genetic alterations.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients affected by primary progressive or relapsing remitting multiple sclerosis * Patient able to provide informed consent Exclusion Criteria: * Individuals with \< 18 years * Patients not affected by primary progressive or relapsing remitting multiple sclerosis

What they're measuring

sequencing of mitochondrial DNA

Timeframe: 3 years

Trial details

NCT IDNCT06025903

SponsorIRCCS San Raffaele

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-09-30

Contact for this trial

Federica Esposito

0226437833 esposito.federica@hsr.it

View on ClinicalTrials.gov More Multiple Sclerosis trials