The Efficacy of Nigella Sativa Oil Mouth Rinse in the Management of Recurrent Minor Aphthous Ulcer

Inclusion Criteria: * All patients should be free from any systemic disease or Behcet syndrome (Atai et al., 2007). * Patients male or female are eligible (Epstein et al., 2018). * Oral pain score of 4 or higher on a scale of 0-10 with 0 representing no pain in the presence of oral ulceration (Epstein et al., 2018). * Patient has only minor aphthous ulcer and its diameter should be less than 1 cm (Atai et al., 2007). * It should had not been passed more than 4 days from beginning of their ulcer (Atai et al., 2007). Exclusion Criteria: * Patients with poor oral hygiene or not willing to perform oral hygiene measures. * Smoking and alcohol use. * Pregnant and lactating females. * Patients with history of any topical or systemic medication or steroid therapy 1 month prior to the investigation (Chaudhuri et al., 2018).