WithdrawnNot Applicable

Does Resistance Training Protocol Change Micromorphology in Achilles Tendinopathy?

Stopped: The study was withdrawn prior to enrollment. The objectives of this study were incorporated into a broader registered and completed study, making this record redundant and no longer necessary to maintain as a separate entry.

Czechia0Started 2023-01-01

Plain-language summary

This work is designed as a prospective cohort study, in which the effects of a protocol of 12-week resistance training loading the Achilles tendon in patients with Achilles tendinopathy (AT) will be monitored. It is estimated that at least 20 patients will participate. In addition, there will be a small control group of healthy participants which will not complete the same protocol, but will be monitored for natural changes in same objectives. Group of patients will be instructed to perform a training protocol.

Who can participate

Age range

18 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * the patient shows symptoms of Achilles tendinopathy (pain, swelling and dysfunction in the area of Achilles tendon), which at least partially limit his quality of life during normal or sporting activities, * the patient is in the age group of 18-60 years, * the patient has difficulties in only one lower limb; the second, asymptomatic limb will be considered the reference, * the patient is not aware of any mechanical damage to the tendon in symptomatic limb in the past (e.g. partial or complete rupture as a result of an injury), * the patient has not undergone any treatment aimed at AS in the last 3 months (surgery, corticoid application, plasma therapy, shock waves, physiotherapy, etc.), objective US examination of AS shows structural changes (expansion, neovascularization, focal hypoechoic areas, etc.). Exclusion Criteria: * patient has been diagnosed with a rheumatic disease or a disease of the central nervous system * patient is aware of mechanical damage to the Achilles tendon as a result of an injury in the past.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in Peak Spatial Frequency Radius at the site of Pathology

Timeframe: Change of initial values at 26 weeks follow up after beginning of the therapy.

Change in Tendon Diameter at the Place of Maximum Tendon Width

Timeframe: Change of initial values at 26 weeks follow up after beginning of the therapy.

Trial details

NCT IDNCT06009536

SponsorUniversity Hospital, Motol

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-05-01

View on ClinicalTrials.gov More Achilles Tendinopathy trials

Plain-language summary

Who can participate

Age range

18 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Change in Peak Spatial Frequency Radius at the site of Pathology

Timeframe: Change of initial values at 26 weeks follow up after beginning of the therapy.

Change in Tendon Diameter at the Place of Maximum Tendon Width

Timeframe: Change of initial values at 26 weeks follow up after beginning of the therapy.