The primary objective of this study will be to evaluate the drug-drug interaction potential of CCX168 with concomitant medications, as either a perpetrator or a victim, following oral administration of CCX168 to healthy participants.
Age range
18 Years – 55 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Cohort A: Maximum Plasma Concentration (Cmax) of Midazolam
Timeframe: Up to Day 13
Cohort A: Cmax of Celecoxib
Timeframe: Up to Day 13
Cohort A: Time of Cmax (Tmax) of Midazolam
Timeframe: Up to Day 13
Cohort A: Tmax of Celecoxib
Timeframe: Up to Day 13
Cohort A: Area under the plasma concentration-time curve (AUC) from Time 0 to infinity of Midazolam
Timeframe: Up to Day 13
Cohort A: AUC from Time 0 to infinity of Celecoxib
Timeframe: Up to Day 13
Cohort A: Apparent Terminal Half Life of Midazolam
Timeframe: Up to Day 13
Cohort A: Apparent Terminal Half Life of Celecoxib
Timeframe: Up to Day 13
Cohort A: Cmax of CCX168
Timeframe: Day 15 up to Day 19
Cohort A: Tmax of CCX168
Timeframe: Day 15 up to Day 19
Cohort A: AUC Over the Dosing Interval of CCX168
Timeframe: Day 15 up to Day 19
Cohort B: Cmax of CCX168
Timeframe: Up to Day 14
Cohort B: Tmax of CCX168
Timeframe: Up to Day 14
Cohort B: AUC from Time 0 to infinity of CCX168
Timeframe: Up to Day 14
Cohort B: Apparent Terminal Half Life of CCX168
Timeframe: Up to Day 14