RecruitingPhase 3

Effect of PRP, PPP, & BMAC on Functional Outcomes Following Hip Arthroscopy for Acetabular Labral Pathologies

United States160 participantsStarted 2023-08-30

Plain-language summary

The goal of this clinical trial is to assess the effect of PRP/PPP/BMAC application on functional outcomes after hip arthroscopy to address acetabular labral pathologies. The main questions it aims to answer are: 1. Does PRP/PPP/BMAC application improve functional outcomes after hip arthroscopy to address acetabular labral pathologies? 2. Does PRP/PPP/BMAC application reduce the arthritic burden as measured by functional outcomes following hip arthroscopy to address labral pathologies with concomitant PRP/PPP/BMAC application?

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age: \> or equal to 18 years * Clinically indicated for hip arthroscopy (by the study PI) to address a labral pathology * Willingness to participate, amenable to randomization into either treatment arm of the research study, and the ability to understand \& sign the informed consent document Exclusion Criteria: * Non-English speaking (PROM surveys are only validated in English) * Prior same site (i.e., ipsilateral hip) surgery, including but not limited to previous hip arthroscopy, core decompression, or periacetabular osteotomies

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Pain Level

Timeframe: Baseline (pre-operative), 3 months, 6 months, 12 months, and 24 months

Modified Harris Hip Score (mHHS)

Timeframe: Baseline (pre-operative), 3 months, 6 months, 12 months, and 24 months

International Hip Outcome Tool-12 (iHOT-12)

Timeframe: Baseline (pre-operative), 3 months, 6 months, 12 months, and 24 months

Non-Arthritic Hip Score (NAHS)

Timeframe: Baseline (pre-operative), 3 months, 6 months, 12 months, and 24 months

Hip Outcome Score (HOS)

Timeframe: Baseline (pre-operative), 3 months, 6 months, 12 months, and 24 months

Kerlan-Jobe Orthopaedic Clinic Athletic Hip Score

Timeframe: Baseline (pre-operative), 3 months, 6 months, 12 months, and 24 months

Visual Analog Scale (VAS) Pain Score

Timeframe: Baseline (pre-operative), 3 months, 6 months, 12 months, and 24 months

Trial details

NCT IDNCT06003101

SponsorMassachusetts General Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-08-30

Contact for this trial

Scott D. Martin, MD

617-732-5329 sdmartin@mgh.harvard.edu

View on ClinicalTrials.gov More Acetabular Labrum Tear trials

Plain-language summary

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Pain Level

Timeframe: Baseline (pre-operative), 3 months, 6 months, 12 months, and 24 months

Modified Harris Hip Score (mHHS)

Timeframe: Baseline (pre-operative), 3 months, 6 months, 12 months, and 24 months

International Hip Outcome Tool-12 (iHOT-12)

Timeframe: Baseline (pre-operative), 3 months, 6 months, 12 months, and 24 months

Non-Arthritic Hip Score (NAHS)

Timeframe: Baseline (pre-operative), 3 months, 6 months, 12 months, and 24 months

Hip Outcome Score (HOS)

Timeframe: Baseline (pre-operative), 3 months, 6 months, 12 months, and 24 months

Kerlan-Jobe Orthopaedic Clinic Athletic Hip Score

Timeframe: Baseline (pre-operative), 3 months, 6 months, 12 months, and 24 months

Visual Analog Scale (VAS) Pain Score

Timeframe: Baseline (pre-operative), 3 months, 6 months, 12 months, and 24 months