Transfer of Feces in Ulcerative Colitis 2

Inclusion Criteria: * Age ≥18 and \<70 * Ability to give informed consent * Established ulcerative colitis with known involvement of the left colon according to the Lennard-Jones criteria * Partial mayo score of ≥ 3 and calprotectin \> 250 * Full Mayo score 5-9 * Endoscopic Mayo score of ≥2 in either the rectum or sigmoid upon screening sigmoidoscopy * Stable dose of thiopurines or , 5-ASA, or budesonide in preceding 8 weeks. * Stable dose of budesonide in preceding 2 weeks. * Prednisone use ≤15mg/day in preceding 2 weeks with a mandatory taper of 5 mg per week starting from week 4. * Women need to use reliable contraceptives during participation in the study * Alkaline phosphatase \> 1.5 x ULN in the subgroup of PSC/UC patients. Exclusion Criteria: * Condition leading to profound immunosuppression * For example: HIV, infectious diseases leading to immunosuppression, bone marrow malignancies * Use of systemic chemotherapy * Child-Pugh B liver cirrhosis * Anti-TNFα treatment in preceding 2 months * Vedolizumab treatment in preceding 2 months * Tofacitinib treatment in preceding 2 months * Ustekinumab treatment in preceding 2 months * Cyclosporine treatment in preceding 4 weeks * Use of Methotrexate in preceding 2 months * Prednisolone dose \> 15 mg/day in preceding 2 weeks * Use of topical therapy in preceding 2 weeks * Life expectancy \< 12 months * Difficulty with swallowing * Use of systemic antibiotics in preceding 4 weeks * Use of probiotic treatment in precedin…