S-adenosylhomocysteine (SAH) is the end-product of methylation reactions in the body and the precursor to homocysteine. Elevated SAH in the blood is a reflection of the dysregulation of what is known as the S-adenosylmethionine (SAM) cycle and has been associated with poor health outcomes. The SAM cycle is a series of reversible reactions necessary for the regulation of many processes in the body. The goal of this clinical trial is to assess the ability of a dietary supplement to support healthy plasma SAH levels in individuals with high plasma SAH. Participants in the study will attend a total of 4 clinic visits and consume study product daily for 12 weeks.
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To determine the effect of the Test Product (TP) compared to placebo on plasma S-adenosylmethionine (SAM) concentration.
Timeframe: 12 weeks
To determine the effect of the TP compared to placebo on plasma S-adenosylhomocysteine (SAH) concentration.
Timeframe: 12 weeks
To determine the effect of the TP compared to placebo on plasma homocysteine concentration.
Timeframe: 12 weeks
To determine the effect of the TP compared to placebo on plasma cystathionine concentration.
Timeframe: 12 weeks
To determine the effect of the TP compared to placebo on plasma cysteine concentration.
Timeframe: 12 weeks
To determine the effect of the TP compared to placebo on plasma methionine concentration.
Timeframe: 12 weeks