Multifaceted Comparison of Ultrasound-guided Ablation and Laparoscopic Adrenalectomy for Aldoster… (NCT05991856) | Clinical Trial Compass
RecruitingNot Applicable
Multifaceted Comparison of Ultrasound-guided Ablation and Laparoscopic Adrenalectomy for Aldosterone-producing Adenoma
China45 participantsStarted 2020-01-01
Plain-language summary
The purpose of this study is to retrospectively and prospectively analyze the efficacy and safety of ultrasound-guided radiofrequency ablation and laparoscopic adrenalectomy in the treatment of aldosterone-producing adenoma (APA). It is planned to retrospectively collect 30 patients with adrenal radiofrequency ablation for APA and 15 patients with age - and sex-matched laparoscopic adrenalectomy for APA in our hospital from January 2020 to June 2024, and continue to follow up for 3 years.
Who can participate
Age range18 Years
SexALL
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Inclusion criteria
✓. APA was confirmed with unilateral lesions;
✓. Benign tumor without adrenal metastasis and endovascular tumor embolus;
✓. Receive ultrasound-guided adrenal RFA treatment or laparoscopic resection, and sign the informed consent for surgery;
✓. Age ≥ 18;
✓. Age ≥ 40 years old should meet the following criteria: blood potassium ≤3.5mmol/L; PAC≥20ng/dL; PRC≤5μIU/mL; A unilateral adrenal nodule of 10mm or more was completely normal on the opposite side.
Exclusion criteria
✕. Bilateral adrenal diseases;
✕. Multiple adrenal tumors;
✕. Other adrenal diseases, such as adrenal hyperplasia, Cushing's syndrome, pheochromocytoma, etc.;
✕. Imaging suggests that the tumor may be difficult to reach;