The purpose of this study is to evaluate the safety, reactogenicity and immunogenicity of 2 formulations of Herpes Simplex Virus (HSV)-Targeted Immunotherapy (HSVTI) in HSV-2 seronegative ethnic Japanese adults aged 18-40 years.
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Number of Participants Reporting Any Solicited Administration Site Events
Timeframe: During the 7 days (including the day of vaccination) following vaccination at Day 1
Number of Participants Reporting Any Solicited Administration Site Events
Timeframe: During the 7 days (including the day of vaccination) following vaccination at Day 29
Number of Participants Reporting Any Solicited Systemic Events
Timeframe: During the 7 days (including the day of vaccination) following vaccination at Day 1
Number of Participants Reporting Any Solicited Systemic Events
Timeframe: During the 7 days (including the day of vaccination) following vaccination at Day 29
Number of Participants Reporting Any Unsolicited Adverse Events (AEs)
Timeframe: During the 28 days (including the day of vaccination) following vaccination at Day 1
Number of Participants Reporting Any Unsolicited AEs
Timeframe: During the 28 days (including the day of vaccination) following vaccination at Day 29
Number of Participants Reporting Any Medically Attended Events (MAEs)
Timeframe: From Day 1 (dose 1) up to Day 57 (28 days post dose 2)
Number of Participants Reporting Any Serious Adverse Events (SAEs)
Timeframe: From Day 1 (dose 1) up to Day 57 (28 days post dose 2)
Number of Participants Reporting Any Newly Diagnosed Potential Immune-Mediated Diseases (pIMDs)
Timeframe: From Day 1 (dose 1) up to Day 57 (28 days post dose 2)
Number of Participants Reporting Any Exacerbation of Pre-existing pIMDs
Timeframe: From Day 1 (dose 1) up to Day 57 (28 days post dose 2)
Number of Participants Reporting Any Hematological and Biochemical Laboratory Abnormalities
Timeframe: At Day 1 (pre-study intervention administration)
Number of Participants Reporting Any Hematological and Biochemical Laboratory Abnormalities
Timeframe: At Day 8 (7 days post dose 1)
Number of Participants Reporting Any Hematological and Biochemical Laboratory Abnormalities
Timeframe: At Day 29 (28 days post dose 1)
Number of Participants Reporting Any Hematological and Biochemical Laboratory Abnormalities
Timeframe: At Day 36 (7 days post dose 2)
Number of Participants Reporting Any Hematological and Biochemical Laboratory Abnormalities
Timeframe: At Day 57 (28 days post dose 2)